The chess game in Blade Runner is a tribute to one of the most famous games in chess history, known as the "Immortal Game." This epic game took place at the London Tournament in 1851 between Adolf Anderssen and Lionel Kieseritzky and became famous primarily for Anderssen's daring sacrifices, including two rooks and the queen, to secure a decisive victory.

Returning to the setting of Blade Runner, this chess game symbolizes the conflict between humans and replicants. Humans are willing to sacrifice their weaker pieces to achieve victory, while replicants are willing to sacrifice themselves to attain immortality.

Here's the game:

1. e4 e5
2. f4 exf4
3. Bc4 Qh4+
4. Kf1 b5
5. Bxb5 Nf6
6. Nf3 Qh6
7. d3 Nh5
8. Nh4 Qg5
9. Nf5 c6
10. g4 Nf6
11. Rg1 cxb5
12. h4 Qg6
13. h5 Qg5
14. Qf3 Ng8
15. Bxf4 Qf6
16. Nc3 Bc5
17. Nd5 Qxb2
18. Bd6 Bxg1

It's from this move (18... Bxg1) that Black's defeat ensues. Wilhelm Steinitz suggested in 1879 that a better move would have been 18... Qxa1+; likely moves to follow are 19. Ke2 Qb2 20. Kd2 Bxg1, leading to a different outcome. White wins with 19. e5 Qxa1+ 20. Ke2 Na6 21. Nxg7+ Kd8 22. Qf6+ Nxf6 23. Be7# 1-0.